Carolina Panthers quarterback Cam Newton had a good time jawing with the fans during joint practices with the Tennessee Titans this past week in Nashville, Tennessee.

“I can’t right now, brother,’’ Newton told fans wanting a moment of his time Thursday. Kelvin Benjamin Jerseys “I’m working. I’ve got to keep my lights on. I’ve got to keep my bills paid. You know what I’m saying?’’

Newton didn’t do much to pay the bills during Wednesday and Thursday practices as he continued to rehab his surgically repaired shoulder. Luke Kuechly Jerseys He threw some in individual drills and 7-on-7 drills but didn’t participate in team drills.

He won’t play in Saturday's 3 p.m. preseason game at Nissan Stadium, where the 2015 NFL MVP introduced the world to the dab two years ago.

But there are plenty of other things to keep an eye on as the Panthers try to run their preseason record to 2-0. Here are five things:

Offensive consistency -- Coach Ron Rivera used the word “terrible’’ to describe all of the bad plays made Thursday. Star Lotulelei Jerseys He wasn’t happy with the rhythm, the dropped passes and the fundamental mistakes. Even without Newton and several other stars, Rivera told players that if they expected to be great, “you’ve got to be great every day.’’ He says that even if it’s backup quarterback Derek Anderson running the offense and lesser-known receivers catching passes, as was the case Thursday. Cam Newton Jerseys There are no guarantees Newton will be ready for the opener, even though that is the target. So it’s imperative the offense look sharp with Anderson & Co.

What’s next, McCaffrey? Rivera wasn’t the only one unhappy with Thursday’s practice. Even rookie Christian McCaffrey said the Panthers have “higher standards.” McCaffrey set the bar pretty high for himself in the preseason opener, rushing for 33 yards on seven carries. Greg Olsen Jerseys He almost broke a couple of runs. What he didn’t do was catch a pass, one of the big reasons he was selected with the eighth pick in the draft. While the Panthers don’t want to show their entire game plan for McCaffrey before the opener, they’ll want to see what the former Stanford star can do in the passing game against an opponent other than his own defense. Getting him one-on-one in the open field will be a big part of this offense no matter who is playing quarterback.

WHAT IS THE COLON?

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The colon

Is the last part of the digestive system in most vertebrates; it extracts water and salt from solid wastes before they are eliminated from the body, and is the site in which flora-aided (largely bacterial) fermentation of unabsorbed material occurs. Unlike the small intestine, the colon does not play a major role in absorption of foods and nutrients. However, the colon does absorb water, sodium and some fat-soluble vitamins.
In mammals, the colon consists of four sections: the ascending colon, the transverse colon, the descending colon, and the sigmoid colon (the proximal colon usually refers to the ascending colon and transverse colon). The colon, cecum, and rectum make up the large intestine.

Anatomy

The location of the parts of the colon is either in the abdominal cavity or behind it in the retroperitoneum. The colon in those areas is fixed in location.
The haustra of the colon are the small pouches caused by sacculation, which give the colon its segmented appearance. The taenia coli runs the length of the large intestine. Because the taenia coli is shorter than the intestine, the colon becomes sacculated between the taenia, forming the haustra.

Blood supply and lymphatic’s

Arterial supply to the colon comes from branches of the superior mesenteric artery (SMA) and inferior mesenteric artery (IMA). Flow between these two systems communicates via a "marginal artery" that runs parallel to the colon for its entire length. Historically, it has been believed that the arc of Riolan, or the meandering mesenteric artery (of Moskowitz), is a variable vessel connecting the proximal SMA to the proximal IMA that can be extremely important if either vessel is occluded. However, recent studies conducted with improved imaging technology have questioned the actual existence of this vessel, with some experts calling for the abolition of the terms from future medical literature.
Venous drainage usually mirrors colonic arterial supply, with the inferior mesenteric vein draining into the splenic vein, and the superior mesenteric vein joining the splenic vein to form the hepatic portal vein that then enters the liver.
Lymphatic drainage from the entire colon and proximal two-thirds of the rectum is to the paraaortic lymph nodes that then drain into the cisterna chyli. The lymph from the remaining rectum and anus can either follow the same route, or drain to the internal iliac and superficial inguinal nodes. The pectinate line only roughly marks this transition.

Ascending colon

The ascending colon, on the right side of the abdomen, is about 13 cm long in humans.[3] It is the part of the colon from the cecum to the hepatic flexure (the turn of the colon by the liver). It is secondarily retroperitoneal in most humans. In ruminant grazing animals, the cecum empties into the spiral colon.

Anteriorly it is related to the coils of small intestine, the right edge of the greater omentum, and the anterior abdominal wall. Posteriorly, it is related to the iliacus, the iliolumbar ligament, the quadratus lumborum, the transverse abdominis, the diaphragm at the tip of the last rib; the lateral cutaneous, ilioinguinal, and iliohypogastric nerves; the iliac branches of the iliolumbar vessels, the fourth lumbar artery, and the right kidney.
The ascending colon is supplied by parasympathetic fibers of the vagus nerve (CN X).

Arterial supply of the ascending colon comes from the ileocolic artery and right colic artery, both branches of the SMA. While the ileocolic artery is almost always present, the right colic may be absent in 5–15% of individuals.

Transverse colon

The transverse colon is the part of the colon from the hepatic flexure to the splenic flexure (the turn of the colon by the spleen). The transverse colon hangs off the stomach, attached to it by a wide band of tissue called the greater omentum. On the posterior side, the transverse colon is connected to the posterior abdominal wall by a mesentery known as the transverse mesocolon.

The transverse colon is encased in peritoneum, and is therefore mobile (unlike the parts of the colon immediately before and after it). Cancers form more frequently further along the large intestine as the contents become more solid (water is removed) in order to form feces.

The proximal two-thirds of the transverse colon is perfused by the middle colic artery, a branch of SMA, while the latter third is supplied by branches of the IMA. The "watershed" area between these two blood supplies, which represents the embryologic division between the mid-gut and hindgut, is an area sensitive to ischemia.

Descending colon

The descending colon is the part of the colon from the splenic flexure to the beginning of the sigmoid colon. The function of the descending colon in the digestive system is to store food that will be emptied into the rectum. It is retroperitoneal in two-thirds of humans. In the other third, it has a (usually short) mesentery. The arterial supply comes via the left colic artery.

Sigmoid colon

The sigmoid colon is the part of the large intestine after the descending colon and before the rectum. The name sigmoid means S-shaped (see sigmoid). The walls of the sigmoid colon are muscular, and contract to increase the pressure inside the colon, causing the stool to move into the rectum.

The sigmoid colon is supplied with blood from several branches (usually between 2 and 6) of the sigmoid arteries, a branch of the IMA. The IMA terminates as the superior rectal artery.

Sigmoidoscopy is a common diagnostic technique used to examine the sigmoid colon.

Redundant colon

One variation on the normal anatomy of the colon occurs when extra loops form, resulting in a longer than normal organ. This condition, referred to as redundant colon, typically has no direct major health consequences, though rarely volvulus occurs resulting in obstruction and requiring immediate medical attention.[4] A significant indirect health consequence is that use of a standard adult colonoscope is difficult and in some cases impossible when a redundant colon is present, though specialized variants on the instrument (including the pediatric variant) are useful in overcoming this problem.[5]

Standing gradient osmosis

Water absorption at the colon typically proceeds against a transmucosal osmotic pressure gradient. The standing gradient osmosis is a term used to describe the reabsorption of water against the osmotic gradient in the intestines. This hypertonic fluid creates an osmotic pressure that drives water into the lateral intercellular spaces by osmosis via tight junctions and adjacent cells, which then in turn moves across the basement membrane and into the capillaries.

Function

There are differences in the large intestine between different organisms. The large intestine is mainly responsible for storing waste, reclaiming water, maintaining the water balance, absorbing some vitamins, such as vitamin K, and providing a location for flora-aided fermentation.

By the time the chyme has reached this tube, most nutrients and 90% of the water have been absorbed by the body. At this point some electrolytes like sodium, magnesium, and chloride are left as well as indigestible parts of ingested food (e.g., a large part of ingested amylose, protein which has been shielded from digestion heretofore, and dietary fiber, which is largely indigestible carbohydrate in either soluble or insoluble form). As the chyme moves through the large intestine, most of the remaining water is removed, while the chyme is mixed with mucus and bacteria (known as gut flora), and becomes feces. The ascending colon receives fecal material as a liquid. The muscles of the colon then move the watery waste material forward and slowly absorb all the excess water. The stools get to become semi solid as they move along into the descending colon[6] The bacteria break down some of the fiber for their own nourishment and create acetate, propionate, and butyrate as waste products, which in turn are used by the cell lining of the colon for nourishment. No protein is made available. In humans, perhaps 10% of the undigested carbohydrate thus becomes available; in other animals, including other apes and primates, who have proportionally larger colons, more is made available, thus permitting a higher portion of plant material in the diet. This is an example of a symbiotic relationship and provides about one hundred calories a day to the body. The large intestine produces no digestive enzymes  chemical digestion is completed in the small intestine before the chyme reaches the large intestine. The pH in the colon varies between 5.5 and 7 (slightly acidic to neutral).

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The Colon

The colon has been referred to as the sewer system of the body. It is the place where we store the waste material that most of us would rather not think about ...  Read More

Katie Couric's Story

Katie's husband, Jay Monahan, died of colon cancer in 1998 at age 42. He was diagnosed at age 41. He had no symptoms. Had he been screened earlier, he may have lived a long life. After seeing her husband shuffled from place to place for tests and treatments, and then passing away, Katie was determined to help people get screening tests.